Hound

Overview

  • Characterize all your particles
    Hound is the only tool out there that combines microscopy, Raman and Laser-Induced Breakdown Spectroscopy (LIBS) to count, size, and ID particles by their chemical or elemental fingerprints. With all these capabilities packed into one instrument, Hound gathers up all the info you need about your particles in minutes.

Count
Size
Shape
Chemical ID
Elemental ID

  • Capabilities
  • Specifications
  • Round them up
    Hound lets you prep your sample for any type of analysis. Capture big, visible particles by plucking them from solution, or pour the whole sample through a filter round if they’re small. If you want to keep them in suspension, just pipette the sample onto a wet round. No matter what works best for your samples, the gold-coated surfaces catch everything and cut out all the background noise.
  • Track them down
    Once you’ve snagged all your particles, Hound automatically spots them and sizes them up. It uses bright-field or dark-field imaging, so nothing sneaks by — not even tricky translucent particles like proteins. Hound scans the round and reports the size, shape, morphology and fibrosity of everything within minutes
  • Identify the unknowns
    If you can’t figure out your particle by just size and shape, Hound has extra gear to characterize it. Raman 785 nm is the workhorse laser that can ID most particles. For protein aggregates or particles that have fluorescence, switch to Raman 532 nm. Think you have metals? Blast it with the LIBS laser to identify the particle based on its elements.
  • Teach Hound new tricks
    Raman and LIBS capture the signature from your particles. These unique fingerprints can be saved to a customizable reference database – so the next time you’ll ID it right away. Your images and spectra are stored for reference and reports, and 21 CFR Part 11 software tools help you maintain compliance through data collection and analysis.

Description

Specification

MicroscopyImaging: 5.1 MP color camera, 2048 x 2048 active pixel area


Magnification: 5x, 10x, 20x, 20x w/UV filter (LIBS) and 50x objectives (Raman)


Illumination: Integrated bright-field (all objectives) and dark-field (20x)


Particle size range: 2 μm – 15000 μm (upper end may extend based on applications)


Accuracy: ±5% sizing (magnification dependent), ±10% counting
Raman785 nm: 70 mW, adjustable power, Class 3b laser


532 nm: 30 mW, adjustable power, Class 3b laser


Objective: 50x, 0.5 NA, 10.6 mm WD


Spectral range: 200–3300 cm-1, 6–10 cm-1 resolution (varies across range)


Minimum particle size:2 μm


Database: >150 materials, customizable
LIBS

Laser: 343 nm, >100 μJ pulse energy, 1.0 ns pulse duration, Class 4 laser


Objective: 20x with UV lens, 0.4 NA, 4.1 mm WD


Spectral range: 350–700 nm, 1 nm resolution


Minimum particle size: 20 μm


Database: >50 materials, customizable
Sample mounts Standard: Up to 4 gold-coated filter rounds or nitrocellulose membranes, single microscope slide


Optional: Mount for wet round
Filter roundsMaterial: Gold coated polycarbonate (PC)


Pore size: 0.8, 3, 5 and 10 μm available


Diameter: 25 mm
Wet roundsMaterial: Gold-coated silica glass


Diameter: 51 mm
SoftwareOperating system: Windows 10


Compliance: 21 CFR Part 11 tools included
EnvironmentalTemperature range: 18–28 °C


Humidity: 40–60% relative humidity (non-condensing)
PhysicalWeight: 65 kg


Dimensions: 50 cm W x 60 cm D x 70 cm H
Electrical110–230 V, 500 W
CertificationsNRTL and CE

Overview

  • Characterize all your particles
    Hound is the only tool out there that combines microscopy, Raman and Laser-Induced Breakdown Spectroscopy (LIBS) to count, size, and ID particles by their chemical or elemental fingerprints. With all these capabilities packed into one instrument, Hound gathers up all the info you need about your particles in minutes.

Count
Size
Shape
Chemical ID
Elemental ID

Capabilities

  • Round them up
    Hound lets you prep your sample for any type of analysis. Capture big, visible particles by plucking them from solution, or pour the whole sample through a filter round if they’re small. If you want to keep them in suspension, just pipette the sample onto a wet round. No matter what works best for your samples, the gold-coated surfaces catch everything and cut out all the background noise.
  • Track them down
    Once you’ve snagged all your particles, Hound automatically spots them and sizes them up. It uses bright-field or dark-field imaging, so nothing sneaks by — not even tricky translucent particles like proteins. Hound scans the round and reports the size, shape, morphology and fibrosity of everything within minutes
  • Identify the unknowns
    If you can’t figure out your particle by just size and shape, Hound has extra gear to characterize it. Raman 785 nm is the workhorse laser that can ID most particles. For protein aggregates or particles that have fluorescence, switch to Raman 532 nm. Think you have metals? Blast it with the LIBS laser to identify the particle based on its elements.
  • Teach Hound new tricks
    Raman and LIBS capture the signature from your particles. These unique fingerprints can be saved to a customizable reference database – so the next time you’ll ID it right away. Your images and spectra are stored for reference and reports, and 21 CFR Part 11 software tools help you maintain compliance through data collection and analysis.

Specifications

Description

Specification

MicroscopyImaging: 5.1 MP color camera, 2048 x 2048 active pixel area


Magnification: 5x, 10x, 20x, 20x w/UV filter (LIBS) and 50x objectives (Raman)


Illumination: Integrated bright-field (all objectives) and dark-field (20x)


Particle size range: 2 ?m – 15000 ?m (upper end may extend based on applications)


Accuracy: ±5% sizing (magnification dependent), ±10% counting
Raman785 nm: 70 mW, adjustable power, Class 3b laser


532 nm: 30 mW, adjustable power, Class 3b laser


Objective: 50x, 0.5 NA, 10.6 mm WD


Spectral range: 200–3300 cm-1, 6–10 cm-1 resolution (varies across range)


Minimum particle size: 2 ?m


Database: >150 materials, customizable
LIBSLaser: 343 nm, >100 ?J pulse energy, 1.0 ns pulse duration, Class 4 laser


Objective: 20x with UV lens, 0.4 NA, 4.1 mm WD


Spectral range: 350–700 nm, 1 nm resolution


Minimum particle size: 20 ?m


Database: >50 materials, customizable
Sample mounts Standard: Up to 4 gold-coated filter rounds or nitrocellulose membranes, single microscope slide


Optional: Mount for wet round
Filter roundsMaterial: Gold coated polycarbonate (PC)


Pore size: 0.8, 3, 5 and 10 ?m available


Diameter: 25 mm
Wet roundsMaterial: Gold-coated silica glass


Diameter: 51 mm
SoftwareOperating system: Windows 10


Compliance: 21 CFR Part 11 tools included
EnvironmentalTemperature range: 18–28 °C


Humidity: 40–60% relative humidity (non-condensing)
PhysicalWeight: 65 kg


Dimensions: 50 cm W x 60 cm D x 70 cm H
Electrical110–230 V, 500 W
CertificationsNRTL and CE

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